BRINGING GENETIC TESTING
INTO FOCUS
INTO FOCUS
BRINGING GENETIC TESTING
INTO FOCUS
INTO FOCUS
3X-TGT: The Tech Behind Our Tests
Fusing computer science and biology, 3X Genetics has created a platform that delivers unprecedented scope, accuracy and speed. 3X-TGT enables the precise sequencing of targeted genetic regions, including those necessary to make a comprehensive diagnosis of Repeat Expansion Disorders (REDs).
When Broader Isn’t Better
Conventional whole genome sequencing maps the entire genome, but it struggles with repetitive regions and can miss a significant percentage of genetic disorders. 3X-TGT targets these challenging sequences directly with long-read technology, delivering faster, more accurate diagnoses for conditions that conventional methods routinely miss.
Precision That Makes For Confident Decisions
3X-TGT delivers exact repeat lengths, not estimates or ranges. This precision gives patients, clinicians and researchers the clarity they need to make critical decisions.
The 3X-TGT Process
Computational Biology
Patent-pending algorithms generate optimal assays.
Wet-Lab Validation
Assays are validated through patient testing at our CLIA-licensed laboratory.
Results Reporting
Results are delivered through Kindred Dx, our patient-centric, HIPAA-compliant reporting platform.
What We Measure
- Exact repeat length across the full expansion range, including ultra-long alleles.
- Sequence interruptions within repeat regions
- Methylation and other epigenetic markers
- Somatic mosaicism patterns
- Biomarkers relevant to therapeutic development
How We Deliver It
- Computationally optimized assay design for each disease
- Proprietary sample enrichment paired with long-red sequencing
- Higher precision than TP-PCR and Southern blot
- Faster turnaround through multiplexed workflow
- Results delivered via our Kindred Dx platform